Genetics

Métodos de ensino

Theoretical classes are supported by slide show and other multimedia means, where the discussion of the different syllabus content is encouraged.
Theoretical-practical exercises are performed to improve the understanding and applications of previously acquired theoretical concepts.
Development of practical activities with use of Information Technology tools.
The evaluation will be developed using 1 theoretical exam (100%).

Objetivos de Unidade Curricular

Understand the basic principles of chromosomal theory of heredity, genetic transmission and recombination processes, chromosomal rearrangements and their variation in number.
Understanding the mechanisms of activation/repression of genetic expression.
Identify and understand the fundamental principles of human genetics and its application to health.
Understand the fundamentals of the use of bioinformatics as research tool, interpretation and genomic analysis and sequencing.

Estagios

Nao

Programa

Basic principles of heredity
Gene binding, recombination and mapping
Gene Mutations and DNA Repair
Chromosomal structural changes
Chromosomal Numerical Changes
General principles of gene regulation
Concepts and bases of genetics applied to human health
Notions of Epigenetics: from the genome to the epigenome
Genetic variation in individuals and populations: mutation and polymorphism
Notions of nutrigenomics and pharmacogenetics
Bioinformatics: Main databases and browsers of DNA and RNA sequences, proteins, molecular structures and genomes.

Métodos de Avaliação

Continuous Evaluation

Frequency: 100.0%

Exam Evaluation

Theorical Exam: 100.0%

Itens Bibliograficos

B. A., Pierce. (2016). Genetics – A Conceptual Approach – 6Th Edition. Freeman &Amp; Company, W. H. Isbn-13: 978-1-31-905096-2
H., Leland, M. L., Goldberg, J. A., Fisher. (2015). Genetics – From Genes To Genome – 5Th Edition. Mcgraw-Hill Education. Isbn: 978-0-07-352531-6
W. S., Klug, M. R., Cummings, C. A., Spencer, M. A., Palladino. (2012). Concepts Of Genetics – 10Th Edition. Pearson Education Inc. Isbn-13: 978-0-321-72412-0.
J. Xiong. (2006). Essential Bioinformatics. Cambridge University Press. Isbn-13: 9780521840989.
A. D., Baxevanis, B.f. F., Quellette. (2005). Bioinformatics: A Practical Guide To The Analysis Of Genes And Proteins. Wiley. Isbn-13: 978-0471478782.